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Last updated: 2017/8/13

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MVK Pre-design Chimera RNAi

  • Catalog # : H00004598-R02
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  • Specification
  • Product Description:
  • Homo sapiens mevalonate kinase (mevalonic aciduria) (MVK), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000431
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 4598
  • Gene Name:
  • MVK
  • Gene Alias:
  • FLJ96772,LRBP,MK,MVLK
  • Gene Description:
  • mevalonate kinase
  • Gene Summary:
  • This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • LH receptor mRNA-binding protein,mevalonic aciduria
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