MVK polyclonal antibody (A01)
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More Files
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Western Blot (Cell lysate)
MVK polyclonal antibody (A01), Lot # 051116JC01. Western Blot analysis of MVK expression in NIH/3T3.
Western Blot (Cell lysate)
MVK polyclonal antibody (A01), Lot # 051116JC01 Western Blot analysis of MVK expression in A-431 ( Cat # L015V1 ).
Western Blot detection against Immunogen (37.11 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant MVK.
Immunogen
MVK (AAH16140, 297 a.a. ~ 396 a.a) partial recombinant protein with GST tag.
Sequence
LIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL
Host
Mouse
Reactivity
Human, Mouse
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MVK polyclonal antibody (A01), Lot # 051116JC01. Western Blot analysis of MVK expression in NIH/3T3.Western Blot (Cell lysate)
MVK polyclonal antibody (A01), Lot # 051116JC01 Western Blot analysis of MVK expression in A-431 ( Cat # L015V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — MVK
Entrez GeneID
4598GeneBank Accession#
BC016140Protein Accession#
AAH16140Gene Name
MVK
Gene Alias
FLJ96772, LRBP, MK, MVLK
Gene Description
mevalonate kinase
Gene Ontology
HyperlinkGene Summary
This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. [provided by RefSeq
Other Designations
LH receptor mRNA-binding protein|mevalonic aciduria
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Interactome
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Pathway
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Disease
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