MVD monoclonal antibody (M01), clone 2A7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MVD.
Immunogen
MVD (NP_002452, 301 a.a. ~ 398 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
AYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKP
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.52 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MVD monoclonal antibody (M01), clone 2A7 Western Blot analysis of MVD expression in A-431 ( Cat # L015V1 ).Western Blot (Transfected lysate)
Western Blot analysis of MVD expression in transfected 293T cell line by MVD monoclonal antibody (M01), clone 2A7.
Lane 1: MVD transfected lysate(43.4 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MVD is approximately 0.1ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to MVD on A-431 cell. [antibody concentration 10 ug/ml] -
Gene Info — MVD
Entrez GeneID
4597GeneBank Accession#
NM_002461Protein Accession#
NP_002452Gene Name
MVD
Gene Alias
FP17780, MPD
Gene Description
mevalonate (diphospho) decarboxylase
Omim ID
603236Gene Ontology
HyperlinkGene Summary
The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP. [provided by RefSeq
Other Designations
diphosphomevalonate decarboxylase|mevalonate pyrophosphate decarboxylase
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Interactome
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Pathway
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Disease
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