This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity:
Human
Quality Control Testing:
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of MUTYH transfected lysate using mouse monoclonal anti-MUTYH and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-MUTYH.
Supplied Product:
Antibody pair set content: 1. Antibody pair for IP: mouse monoclonal anti-MUTYH (300 ug) 2. Antibody pair for WB: rabbit polyclonal anti-MUTYH (50 ul)
Storage Instruction:
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations:
A/G-specific adenine DNA glycosylase,OTTHUMP00000009096,OTTHUMP00000009098,OTTHUMP00000009101,OTTHUMP00000009102,mutY homolog