MUT purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MUT protein.
Immunogen
MUT (AAH16282.1, 1 a.a. ~ 750 a.a) full-length human protein.
Sequence
MLRAKNQLFLLSPHYLRQVKESSGSRLIQQRLLHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDTVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLEKKQQSV
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
MUT MaxPab polyclonal antibody. Western Blot analysis of MUT expression in human liver.Western Blot (Cell lysate)
MUT MaxPab polyclonal antibody. Western Blot analysis of MUT expression in A-431.Western Blot (Transfected lysate)
Western Blot analysis of MUT expression in transfected 293T cell line (H00004594-T01) by MUT MaxPab polyclonal antibody.
Lane 1: MUT transfected lysate(82.5 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — MUT
Entrez GeneID
4594GeneBank Accession#
BC016282.1Protein Accession#
AAH16282.1Gene Name
MUT
Gene Alias
MCM
Gene Description
methylmalonyl Coenzyme A mutase
Gene Ontology
HyperlinkGene Summary
This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria. [provided by RefSeq
Other Designations
OTTHUMP00000039926
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Interactome
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Pathway
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Disease
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Publication Reference
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Human MMAA induces the release of inactive cofactor and restores methylmalonyl-CoA mutase activity through their complex formation.
Takahashi-Iñiguez T, González-Noriega A, Michalak C, Flores ME.
Biochimie 2017 Sep; 142:191.
Application:IF, Human, Human fibroblast GMO2784 cells .
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Human MMAA induces the release of inactive cofactor and restores methylmalonyl-CoA mutase activity through their complex formation.
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