TRIM37 monoclonal antibody (M01), clone 2D11
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant TRIM37.
Immunogen
TRIM37 (NP_056109, 865 a.a. ~ 964 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GHLEGLQMTDLENNSETGELQPVLPEGASAAPEEGMSSDSDIECDTENEEQEEHTSVGGFHDSFMVMTQPPDEDTHSSFPDGEQIGPEDLSFNTDENSGR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (77); Rat (77)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TRIM37 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — TRIM37
Entrez GeneID
4591GeneBank Accession#
NM_015294Protein Accession#
NP_056109Gene Name
TRIM37
Gene Alias
KIAA0898, MUL, POB1, TEF3
Gene Description
tripartite motif-containing 37
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq
Other Designations
RING-B-box-coiled-coil protein|tripartite motif-containing 37 protein
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Interactomes
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Pathways
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