MUC2 monoclonal antibody (M03), clone 4A4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MUC2.
Immunogen
MUC2 (NP_002448, 5081 a.a. ~ 5179 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
TTEVSYAGCTKTVLMNHCSGSCGTFVMYSAKAQALDHSCSCCKEEKTSQREVVLSCPNGGSLTHTYTHIESCQCQDTVCGLPTGTSRRARRSPRHLGSG*
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (69%)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — MUC2
Entrez GeneID
4583GeneBank Accession#
NM_002457Protein Accession#
NP_002448Gene Name
MUC2
Gene Alias
MLP, SMUC
Gene Description
mucin 2, oligomeric mucus/gel-forming
Omim ID
158370Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq
Other Designations
mucin 2|mucin 2, intestinal/tracheal|mucin-like protein
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Interactome
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Pathway
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Disease
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