MUC1 (Human) Matched Antibody Pair
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human MUC1.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88%); Rat (80%)
Quality Control Testing
Standard curve using recombinant protein ( H00004582-Q01 ) as an analyte.
Sandwich ELISA detection sensitivity ranging from 3 ng/ml to 100 ng/ml.
Supplied Product
Antibody pair set content:
1. Capture antibody: mouse monoclonal anti-MUC1, IgG2a Kappa (100 ug)
2. Detection antibody: biotinylated mouse monoclonal anti-MUC1, IgG2b Kappa (50 ug)
*Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Recombinant protein)
ELISA Pair (Transfected lysate)
Standard curve using MUC1 293T overexpression lysate (non-denatured) as an analyte. Sandwich ELISA detection sensitivity ranging from approximately 27x to 3x dilution of the MUC1 293T overexpression lysate (non-denatured). -
Gene Info — MUC1
Entrez GeneID
4582Gene Name
MUC1
Gene Alias
CD227, EMA, H23AG, MAM6, PEM, PEMT, PUM
Gene Description
mucin 1, cell surface associated
Omim ID
158340Gene Ontology
HyperlinkGene Summary
This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq
Other Designations
DF3 antigen|H23 antigen|MUC-1/SEC|MUC-1/X|MUC1/ZD|OTTHUMP00000033787|OTTHUMP00000033790|OTTHUMP00000033795|breast carcinoma-associated antigen DF3|episialin|mucin 1|mucin 1, transmembrane|peanut-reactive urinary mucin|polymorphic epithelial mucin|tumor as
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Interactome
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Disease
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