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NUDT1 (Human) IP-WB Antibody Pair

  • Catalog # : H00004521-PW1
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00004521-PW1
    Immunoprecipitation of NUDT1 transfected lysate using rabbit polyclonal anti-NUDT1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-NUDT1.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-NUDT1 (300 ul)
    2. Antibody pair for WB: mouse polyclonal anti-NUDT1 (50 ul)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Entrez GeneID:
  • 4521
  • Gene Name:
  • NUDT1
  • Gene Alias:
  • MTH1
  • Gene Description:
  • nudix (nucleoside diphosphate linked moiety X)-type motif 1
  • Gene Summary:
  • Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described. [provided by RefSeq
  • Other Designations:
  • 7,8-dihydro-8-oxoguanine triphosphatase,8-oxo-7,8-dihydrodeoxyguanosine triphosphatase,8-oxo-7,8-dihydroguanosine triphosphatase,8-oxo-dGTPase,OTTHUMP00000024690,OTTHUMP00000115537,OTTHUMP00000115538,OTTHUMP00000115539,OTTHUMP00000115540,mutT human homolo
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