MTF1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human MTF1 partial ORF ( NP_005946, 41 a.a. - 140 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
GTVYDRTTVLIEQDPGTLEDEDDDGQCGEHLPFLVGGEEGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQSECPETKRKEVKRY
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MTF1
Entrez GeneID
4520GeneBank Accession#
NM_005955Protein Accession#
NP_005946Gene Name
MTF1
Gene Alias
MGC23036, MTF-1, ZRF
Gene Description
metal-regulatory transcription factor 1
Omim ID
600172Gene Ontology
HyperlinkGene Summary
This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq
Other Designations
MRE-binding transcription factor-1|OTTHUMP00000004731|metal-responsive transcription factor 1|zinc regulatory factor
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Interactome
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Disease
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