MSX2 monoclonal antibody (M10), clone 1E8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant MSX2.
Immunogen
MSX2 (AAH15509.1, 1 a.a. ~ 133 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKEASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPGRYSPPPRHTSPTT
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (40.26 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MSX2 expression in transfected 293T cell line by MSX2 monoclonal antibody (M10), clone 1E8.
Lane 1: MSX2 transfected lysate(28.9 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Immunoprecipitation
Immunoprecipitation of MSX2 transfected lysate using anti-MSX2 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with MSX2 MaxPab rabbit polyclonal antibody.ELISA
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Gene Info — MSX2
Entrez GeneID
4488GeneBank Accession#
BC015509Protein Accession#
AAH15509.1Gene Name
MSX2
Gene Alias
CRS2, FPP, HOX8, MSH, PFM, PFM1
Gene Description
msh homeobox 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq
Other Designations
msh homeo box 2|msh homeobox homolog 2
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Interactome
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Disease
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