MSMB monoclonal antibody (M08), clone 3B11
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant MSMB.
Immunogen
MSMB (AAH05257.1, 1 a.a. ~ 114 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MNVLLGSVVIFATFVTLCNASCYFIPNEGVPGDSTRKCMDLKGNKHPINSEWQTDNCETCTCYETEISCCTLVSTPVGYDKDNCQRIFKKEDCKYIVVEKKDPKKTCSVSEWII
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (43); Rat (46)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.28 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MSMB is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — MSMB
Entrez GeneID
4477GeneBank Accession#
BC005257Protein Accession#
AAH05257.1Gene Name
MSMB
Gene Alias
HPC13, IGBF, MSP, MSPB, PN44, PRPS, PSP, PSP-94, PSP57, PSP94
Gene Description
microseminoprotein, beta-
Omim ID
157145Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the immunoglobulin binding factor family. It is synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma. This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. The expression of the encoded protein is found to be decreased in prostate cancer. Two alternatively spliced transcript variants encoding different isoforms are described for this gene. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000019596|OTTHUMP00000019597|beta-microseminoprotein|immunoglobulin binding factor|prostate secreted seminal plasma protein|prostatic secretory protein 94|seminal plasma beta-inhibin
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Interactome
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Disease
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Publication Reference
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Expression patterns of candidate susceptibility genes HNF1β and CtBP2 in prostate cancer: Association with tumor progression.
Debiais-Delpech C, Godet J, Pedretti N, Bernard FX, Irani J, Cathelineau X, Cussenot O, Fromont G.
Urologic Oncology 2014 May; 32(4):426.
Application:IHC-P, Human, Prostate.
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Novel Prognostic Markers in the Serum of Patients With Castration-Resistant Prostate Cancer Derived From Quantitative Analysis of the Pten Conditional Knockout Mouse Proteome.
Kalin M, Cima I, Schiess R, Fankhauser N, Powles T, Wild P, Templeton A, Cerny T, Aebersold R, Krek W, Gillessen S.
European Urology 2011 Dec; 60(6):1235.
Application:S-ELISA, Human, Serum.
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Expression patterns of candidate susceptibility genes HNF1β and CtBP2 in prostate cancer: Association with tumor progression.
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