Western blot analysis of CITED1 over-expressed 293 cell line, cotransfected with CITED1 Validated Chimera RNAi ( Cat # H00004435-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with CITED1 monoclonal antibody (M01), clone 6G8 (Cat # H00004435-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
This gene encodes a member of the CREB-binding protein/p300-interacting transactivator with Asp/Glu-rich C-terminal domain (CITED) family of proteins. The encoded protein, also known as melanocyte-specific gene 1, may function as a transcriptional coactivator and may play a role in pigmentation of melanocytes. Alternatively spliced transcript variants have been described. [provided by RefSeq