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Last updated: 2016/10/23
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MRE11A monoclonal antibody (M02), clone 3H4-F4

  • Catalog # : H00004361-M02
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a full-length recombinant MRE11A.
  • Immunogen:
  • MRE11A (AAH05241, 1 a.a. ~ 206 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgG2a Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00004361-M02
    Western Blot detection against Immunogen (48.4 KDa) .
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Sandwich ELISA (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
  • Detection limit for recombinant GST tagged MRE11A is 3 ng/ml as a capture antibody.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
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  • Gene Information
  • Entrez GeneID:
  • 4361
  • Gene Name:
  • MRE11A
  • Gene Alias:
  • Gene Description:
  • MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • Gene Summary:
  • This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • AT-like disease,DNA recombination and repair protein,double-strand break repair protein MRE11A,endo/exonuclease Mre11,meiotic recombination 11 homolog A
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