Products

Immunoprecipitation-Western Blot

Entrez GeneID

Gene Name

MPST

Gene Alias

MGC24539, MST, TST2

Gene Description

mercaptopyruvate sulfurtransferase

Omim ID

Gene Ontology

Gene Summary

This protein encoded by this gene catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST, GeneID:7263), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU). Alternatively spliced transcript variants encoding same or different isoforms have been identified for this gene. [provided by RefSeq

Other Designations

3-mercaptopyruvate sulfurtransferase|OTTHUMP00000028670|human liver rhodanese