MPST monoclonal antibody (M01), clone 1B5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MPST.
Immunogen
MPST (NP_001013454.1, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MASPQLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIY
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of MPST transfected lysate using anti-MPST monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with MPST MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MPST is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — MPST
Entrez GeneID
4357GeneBank Accession#
NM_001013436Protein Accession#
NP_001013454.1Gene Name
MPST
Gene Alias
MGC24539, MST, TST2
Gene Description
mercaptopyruvate sulfurtransferase
Omim ID
602496Gene Ontology
HyperlinkGene Summary
This protein encoded by this gene catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST, GeneID:7263), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU). Alternatively spliced transcript variants encoding same or different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
3-mercaptopyruvate sulfurtransferase|OTTHUMP00000028670|human liver rhodanese
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