Western blot analysis of MPP1 over-expressed 293 cell line, cotransfected with MPP1 Validated Chimera RNAi ( Cat # H00004354-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with MPP1 monoclonal antibody (M02), clone 1C3-1D11 (Cat # H00004354-M02 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
Palmitoylated membrane protein 1 is the prototype of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 1 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. [provided by RefSeq
OTTHUMP00000026054,aging-associated gene 12,erythrocyte membrane protein p55,membrane protein, palmitoylated 1 (55kD),palmitoylated membrane protein 1