MPO monoclonal antibody (M01), clone 3E11
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MPO.
Immunogen
MPO (NP_000241, 646 a.a. ~ 745 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWREAS
Host
Mouse
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (85)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MPO monoclonal antibody (M01), clone 3E11. Western Blot analysis of MPO expression in Raw 264.7.Western Blot (Cell lysate)
MPO monoclonal antibody (M01), clone 3E11. Western Blot analysis of MPO expression in Jurkat.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MPO is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — MPO
Entrez GeneID
4353GeneBank Accession#
NM_000250Protein Accession#
NP_000241Gene Name
MPO
Gene Alias
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Gene Description
myeloperoxidase
Gene Ontology
HyperlinkGene Summary
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq
Other Designations
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Interactome
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Disease
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