MNDA 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
MNDA transfected lysate.
Western Blot
Lane 1: MNDA transfected lysate ( 44.88 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-MNDA full-length
Host
Human
Theoretical MW (kDa)
44.88
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-MNDA antibody (H00004332-B01) by Western Blots.
SDS-PAGE Gel
MNDA transfected lysate.
Western Blot
Lane 1: MNDA transfected lysate ( 44.88 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — MNDA
Entrez GeneID
4332GeneBank Accession#
NM_002432.1Protein Accession#
-Gene Name
MNDA
Gene Alias
PYHIN3
Gene Description
myeloid cell nuclear differentiation antigen
Omim ID
159553Gene Ontology
HyperlinkGene Summary
The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq
Other Designations
OTTHUMP00000024384
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Interactome
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