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MMP14 Pre-design Chimera RNAi

  • Catalog # : H00004323-R01
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  • Specification
  • Product Description:
  • Homo sapiens matrix metallopeptidase 14 (membrane-inserted) (MMP14), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_004995
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 4323
  • Gene Name:
  • MMP14
  • Gene Alias:
  • MMP-X1,MT1-MMP,MTMMP1
  • Gene Description:
  • matrix metallopeptidase 14 (membrane-inserted)
  • Gene Summary:
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq
  • Other Designations:
  • matrix metalloproteinase 14,matrix metalloproteinase 14 (membrane-inserted),membrane type 1 metalloprotease,membrane-type matrix metalloproteinase 1,membrane-type-1 matrix metalloproteinase
  • Gene Pathway
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