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MMP13 Validated Chimera RNAi

  • Catalog # : H00004322-R01V
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  • Specification
  • Product Description:
  • Homo sapiens matrix metallopeptidase 13 (collagenase 3) (MMP13), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_002427
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
  • Western blot analysis of MMP13 over-expressed 293 cell line, cotransfected with MMP13 Validated Chimera RNAi ( Cat # H00004322-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with MMP13 monoclonal antibody (M07), clone 3B11 (Cat # H00004322-M07 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
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  • Application Image
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
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  • Gene Information
  • Entrez GeneID:
  • 4322
  • Gene Name:
  • MMP13
  • Gene Alias:
  • CLG3
  • Gene Description:
  • matrix metallopeptidase 13 (collagenase 3)
  • Gene Summary:
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq
  • Other Designations:
  • collagenase 3,matrix metalloproteinase 13,matrix metalloproteinase 13 (collagenase 3)
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