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MMP12 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00004321-T02
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-MMP12 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 54
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-MMP12 antibody (H00004321-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00004321-T02
    MMP12 transfected lysate.
    Western Blot
    QC Testing of H00004321-T02
    Lane 1: MMP12 transfected lysate ( 54.00 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 4321
  • Gene Name:
  • MMP12
  • Gene Alias:
  • HME,MGC138506,MME
  • Gene Description:
  • matrix metallopeptidase 12 (macrophage elastase)
  • Gene Summary:
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq
  • Other Designations:
  • macrophage elastase,macrophage metalloelastase,matrix metalloproteinase 12,matrix metalloproteinase 12 (macrophage elastase)
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