MMP10 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MMP10 protein.
Immunogen
MMP10 (NP_002416.1, 1 a.a. ~ 476 a.a) full-length human protein.
Sequence
MMHLAFLVLLCLPVCSAYPLSGAAKEEDSNKDLAQQYLEKYYNLEKDVKQFRRKDSNLIVKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGHSLAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHELGHSLGLFHSANTEALMYPLYNSFTELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAISTLRGEYLFFKDRYFWRRSHWNPEPEFHLISAFWPSLPSYLDAAYEVNSRDTVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGFPRLIADDFPGVEPKVDAVLQAFGFFYFFSGSSQFEFDPNARMVTHILKSNSWLHC
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (76)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
MMP10 MaxPab polyclonal antibody. Western Blot analysis of MMP10 expression in human pancreas.Western Blot (Cell lysate)
MMP10 MaxPab polyclonal antibody. Western Blot analysis of MMP10 expression in A-431.Western Blot (Transfected lysate)
Western Blot analysis of MMP10 expression in transfected 293T cell line (H00004319-T01) by MMP10 MaxPab polyclonal antibody.
Lane 1: MMP10 transfected lysate(52.36 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — MMP10
Entrez GeneID
4319GeneBank Accession#
NM_002425Protein Accession#
NP_002416.1Gene Name
MMP10
Gene Alias
SL-2, STMY2
Gene Description
matrix metallopeptidase 10 (stromelysin 2)
Omim ID
185260Gene Ontology
HyperlinkGene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq
Other Designations
matrix metalloprotease 10|matrix metalloproteinase 10|matrix metalloproteinase 10 (stromelysin 2)|stromelysin 2|transin 2
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Interactome
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Disease
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Publication Reference
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Identification of candidate circulating cisplatin-resistant biomarkers from epithelial ovarian carcinoma cell secretomes.
Teng PN, Wang G, Hood BL, Conrads KA, Hamilton CA, Maxwell GL, Darcy KM, Conrads TP.
British Journal of Cancer 2014 Jan; 110(1):123.
Application:WB-Ce, Human, A2780, A2780-CP20, OVCAR3, CaOV3, OV90 cells.
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Identification of candidate circulating cisplatin-resistant biomarkers from epithelial ovarian carcinoma cell secretomes.
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