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Last updated: 2017/8/13

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MME (Human) IP-WB Antibody Pair

  • Catalog # : H00004311-PW1
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00004311-PW1
    Immunoprecipitation of MME transfected lysate using rabbit polyclonal anti-MME and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-MME.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-MME (300 ul)
    2. Antibody pair for WB: mouse purified polyclonal anti-MME (50 ug)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Entrez GeneID:
  • 4311
  • Gene Name:
  • MME
  • Gene Alias:
  • CALLA,CD10,DKFZp686O16152,MGC126681,MGC126707,NEP
  • Gene Description:
  • membrane metallo-endopeptidase
  • Gene Summary:
  • This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq
  • Other Designations:
  • atriopeptidase,common acute lymphocytic leukemia antigen,enkephalinase,membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase),membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10),membrane metallo-endopeptidase
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