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Last updated: 2017/8/13

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MAP3K11 rabbit monoclonal antibody

  • Catalog # : H00004296-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human MAP3K11 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human MAP3K11 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human MAP3K11 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4296
  • Gene Name:
  • MAP3K11
  • Gene Alias:
  • MGC17114,MLK-3,MLK3,PTK1,SPRK
  • Gene Description:
  • mitogen-activated protein kinase kinase kinase 11
  • Gene Summary:
  • The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq
  • Other Designations:
  • SH3 domain-containing proline-rich kinase,mixed lineage kinase 3,protein-tyrosine kinase PTK1
  • Gene Pathway
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