MICB 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-MICB full-length
Host
Human
Theoretical MW (kDa)
37.51
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-MICB antibody (H00004277-B01) by Western Blots.
SDS-PAGE Gel
MICB transfected lysate.
Western Blot
Lane 1: MICB transfected lysate ( 37.51 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — MICB
Entrez GeneID
4277GeneBank Accession#
BC044218.1Protein Accession#
AAH44218.1Gene Name
MICB
Gene Alias
PERB11.2
Gene Description
MHC class I polypeptide-related sequence B
Omim ID
602436Gene Ontology
HyperlinkGene Summary
This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. [provided by RefSeq
Other Designations
MHC class I chain-related protein B|MHC class I mic-B antigen|MHC class I molecule|MHC class I-like molecule PERB11.2-IMX|OTTHUMP00000029089|OTTHUMP00000035091|OTTHUMP00000035588|stress inducible class I homolog
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Interactome
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Pathway
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Disease
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