MICB rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MICB peptide using ARM Technology.
Immunogen
A synthetic peptide of human MICB is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MICB peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MICB
Entrez GeneID
4277GeneBank Accession#
MICBGene Name
MICB
Gene Alias
PERB11.2
Gene Description
MHC class I polypeptide-related sequence B
Omim ID
602436Gene Ontology
HyperlinkGene Summary
This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. [provided by RefSeq
Other Designations
MHC class I chain-related protein B|MHC class I mic-B antigen|MHC class I molecule|MHC class I-like molecule PERB11.2-IMX|OTTHUMP00000029089|OTTHUMP00000035091|OTTHUMP00000035588|stress inducible class I homolog
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