MICA DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human MICA DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHRDATQLGFQPLMSDLGSTGSTEGA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — MICA
Entrez GeneID
4276GeneBank Accession#
NM_000247.1Protein Accession#
NP_000238.1Gene Name
MICA
Gene Alias
FLJ60820, MGC111087, PERB11.1
Gene Description
MHC class I polypeptide-related sequence A
Omim ID
600169Gene Ontology
HyperlinkGene Summary
MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. [provided by RefSeq
Other Designations
HLA class I antigen|MHC class I chain-related gene A protein|MHC class I chain-related protein A|OTTHUMP00000029088|OTTHUMP00000035033|OTTHUMP00000035034|Stress inducible class I homolog
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Pathway
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Disease
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