MICA 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-MICA full-length
Host
Human
Theoretical MW (kDa)
42.9
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-MICA antibody (H00004276-B01) by Western Blots.
SDS-PAGE Gel
MICA transfected lysate.
Western Blot
Lane 1: MICA transfected lysate ( 42.9 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — MICA
Entrez GeneID
4276GeneBank Accession#
NM_000247.1Protein Accession#
-Gene Name
MICA
Gene Alias
FLJ60820, MGC111087, PERB11.1
Gene Description
MHC class I polypeptide-related sequence A
Omim ID
600169Gene Ontology
HyperlinkGene Summary
MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. [provided by RefSeq
Other Designations
HLA class I antigen|MHC class I chain-related gene A protein|MHC class I chain-related protein A|OTTHUMP00000029088|OTTHUMP00000035033|OTTHUMP00000035034|Stress inducible class I homolog
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Pathway
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Disease
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