MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. [provided by RefSeq
Other Designations:
HLA class I antigen,MHC class I chain-related gene A protein,MHC class I chain-related protein A,OTTHUMP00000029088,OTTHUMP00000035033,OTTHUMP00000035034,Stress inducible class I homolog