MICA rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MICA peptide using ARM Technology.
Immunogen
A synthetic peptide of human MICA is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MICA peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MICA
Entrez GeneID
4276GeneBank Accession#
MICAGene Name
MICA
Gene Alias
FLJ60820, MGC111087, PERB11.1
Gene Description
MHC class I polypeptide-related sequence A
Omim ID
600169Gene Ontology
HyperlinkGene Summary
MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. [provided by RefSeq
Other Designations
HLA class I antigen|MHC class I chain-related gene A protein|MHC class I chain-related protein A|OTTHUMP00000029088|OTTHUMP00000035033|OTTHUMP00000035034|Stress inducible class I homolog
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Pathway
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Disease
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