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MICA rabbit monoclonal antibody

  • Catalog # : H00004276-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human MICA peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human MICA is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human MICA peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 4276
  • GeneBank Accession#:
  • MICA
  • Gene Name:
  • MICA
  • Gene Alias:
  • FLJ60820,MGC111087,PERB11.1
  • Gene Description:
  • MHC class I polypeptide-related sequence A
  • Gene Summary:
  • MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. [provided by RefSeq
  • Other Designations:
  • HLA class I antigen,MHC class I chain-related gene A protein,MHC class I chain-related protein A,OTTHUMP00000029088,OTTHUMP00000035033,OTTHUMP00000035034,Stress inducible class I homolog
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