MGST2 monoclonal antibody (M01A), clone 1D11
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant MGST2.
Immunogen
MGST2 (AAH25416, 1 a.a. ~ 147 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAQQNCVEFYPIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGYSEAAKKRITGFRLSLGILALLTLLGALGIANSFLDEYLDLNIAKKLRRQF
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of MGST2 transfected lysate using anti-MGST2 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with MGST2 MaxPab rabbit polyclonal antibody.ELISA
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Gene Info — MGST2
Entrez GeneID
4258GeneBank Accession#
BC025416Protein Accession#
AAH25416Gene Name
MGST2
Gene Alias
FLJ27438, GST2, MGC14097, MGST-II
Gene Description
microsomal glutathione S-transferase 2
Omim ID
601733Gene Ontology
HyperlinkGene Summary
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes a protein which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. [provided by RefSeq
Other Designations
OTTHUMP00000164539|microsomal GST-2|microsomal GST-II|truncated microsomal glutathione S-transferase 2
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Interactome
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Pathway
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Disease
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Publication Reference
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Increased Leukotriene C4 Synthesis Accompanied Enhanced Leukotriene C4 Synthase Expression and Activities of Ischemia-Reperfusion-Injured Liver in Rats.
Yang SL, Huang X, Chen HF, Xu D, Chen LJ, Kong Y, Lou YJ.
The Journal of Surgical Research 2007 Mar; 140(1):36.
Application:IHC-P, WB-Ti, Rat, Ischemia–Reperfusion-Injured Liver in Rats.
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Sodium nitroprusside decreased leukotriene C4 generation by inhibiting leukotriene C4 synthase expression and activity in hepatic ischemia-reperfusion injured rats.
Yang SL, Lou YJ.
Biochemical pharmacology 2006 Nov; 73(5):724.
Application:WB, Rat, Hepatic I/R injury rats.
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Increased Leukotriene C4 Synthesis Accompanied Enhanced Leukotriene C4 Synthase Expression and Activities of Ischemia-Reperfusion-Injured Liver in Rats.
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