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MFNG Pre-design Chimera RNAi

  • Catalog # : H00004242-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens manic fringe homolog (Drosophila) (MFNG), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_002405
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 4242
  • Gene Name:
  • MFNG
  • Gene Alias:
  • -
  • Gene Description:
  • MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • Gene Summary:
  • This gene is a member of the fringe gene family which also includes Radical and Lunatic fringe. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq
  • Other Designations:
  • O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase,OTTHUMP00000043697,OTTHUMP00000043698,OTTHUMP00000043700,beta-1,3-N-acetylglucosaminyltransferase manic fringe,manic fringe homolog
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