MFNG purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of MFNG expression in transfected 293T cell line (H00004242-T01) by MFNG MaxPab polyclonal antibody.
Lane 1: MFNG transfected lysate(35.31 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MFNG protein.
Immunogen
MFNG (NP_002396.2, 1 a.a. ~ 321 a.a) full-length human protein.
Sequence
MQCRLPRGLAGALLTLLCMGLLCLRYHLNLSPQRVQGTPELSQPNPGPPKLQLHDVFIAVKTTRAFHRLRLELLLDTWVSRTREQTFVFTDSPDKGLQERLGSHLVVTNCSAEHSHPALSCKMAAEFDTFLASGLRWFCHVDDDNYVNPRALLQLLRAFPLARDVYVGRPSLNRPIHASEPQPHNRTRLVQFWFATGGAGFCINRKLALKMAPWASGSRFMDTSALIRLPDDCTMGYIIECKLGGRLQPSPLFHSHLETLQLLRTAQLPEQVTLSYGVFEGKLNVIKLQGPFSPEEDPSRFRSLHCLLYPDTPWCPQLGAR
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MFNG expression in transfected 293T cell line (H00004242-T01) by MFNG MaxPab polyclonal antibody.
Lane 1: MFNG transfected lysate(35.31 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — MFNG
Entrez GeneID
4242GeneBank Accession#
NM_002405.2Protein Accession#
NP_002396.2Gene Name
MFNG
Gene Alias
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Gene Description
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Omim ID
602577Gene Ontology
HyperlinkGene Summary
This gene is a member of the fringe gene family which also includes Radical and Lunatic fringe. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq
Other Designations
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase|OTTHUMP00000043697|OTTHUMP00000043698|OTTHUMP00000043700|beta-1,3-N-acetylglucosaminyltransferase manic fringe|manic fringe homolog
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Interactome
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Pathway
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Disease
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