MFNG polyclonal antibody (A01)
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More Files
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Western Blot (Tissue lysate)
MFNG polyclonal antibody (A01), Lot # 051207JC01. Western Blot analysis of MFNG expression in human ovarian cancer.
Western Blot detection against Immunogen (34.69 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant MFNG.
Immunogen
MFNG (NP_002396, 214 a.a. ~ 291 a.a) partial recombinant protein with GST tag.
Sequence
WASGSRFMDTSALIRLPDDCTMGYIIECKLGGRLQPSPLFHSHLETLQLLRTAQLPEQVTLSYGVFEGKLNVIKLQGP
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.69 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
MFNG polyclonal antibody (A01), Lot # 051207JC01. Western Blot analysis of MFNG expression in human ovarian cancer.Western Blot (Recombinant protein)
ELISA
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Gene Info — MFNG
Entrez GeneID
4242GeneBank Accession#
NM_002405Protein Accession#
NP_002396Gene Name
MFNG
Gene Alias
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Gene Description
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Omim ID
602577Gene Ontology
HyperlinkGene Summary
This gene is a member of the fringe gene family which also includes Radical and Lunatic fringe. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq
Other Designations
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase|OTTHUMP00000043697|OTTHUMP00000043698|OTTHUMP00000043700|beta-1,3-N-acetylglucosaminyltransferase manic fringe|manic fringe homolog
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Interactome
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Pathway
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Disease
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