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MECP2 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00004204-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-MECP2 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 53.57
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-MECP2 antibody (H00004204-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00004204-T01
    MECP2 transfected lysate.
    Western Blot
    QC Testing of H00004204-T01
    Lane 1: MECP2 transfected lysate ( 53.57 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 4204
  • Gene Name:
  • MECP2
  • Gene Alias:
  • AUTSX3,DKFZp686A24160,MRX16,MRX79,MRXS13,MRXSL,PPMX,RTS,RTT
  • Gene Description:
  • methyl CpG binding protein 2 (Rett syndrome)
  • Gene Summary:
  • DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000026021,methyl CpG binding protein 2
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