ADAM11 monoclonal antibody (M01), clone 3D4
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More Files
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Western Blot (Tissue lysate)
ADAM11 monoclonal antibody (M01), clone 3D4. Western Blot analysis of ADAM11 expression in human colon.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ADAM11 is approximately 0.1ng/ml as a capture antibody.
Western Blot detection against Immunogen (37.18 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ADAM11.
Immunogen
ADAM11 (NP_002381, 230 a.a. ~ 333 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GHPTVHSETKYVELIVINDHQLFEQMRQSVVLTSNFAKSVVNLADVIYKEQLNTRIVLVAMETWADGDKIQVQDDLLETLARLMVYRREGLPEPSDATHLFSGR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.18 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
ADAM11 monoclonal antibody (M01), clone 3D4. Western Blot analysis of ADAM11 expression in human colon.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ADAM11 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — ADAM11
Entrez GeneID
4185GeneBank Accession#
NM_002390Protein Accession#
NP_002381Gene Name
ADAM11
Gene Alias
MDC
Gene Description
ADAM metallopeptidase domain 11
Omim ID
155120Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq
Other Designations
a disintegrin and metalloproteinase domain 11|metalloproteinase-like, disintegrin-like, cysteine-rich protein
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Interactome
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Disease
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