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MCP Pre-design Chimera RNAi

  • Catalog # : H00004179-R22
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) (MCP), transcript variant i, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_172355
  • Target Region:
  • 3' Untranslated Region (3'UTR)
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.
    The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 4179
  • Gene Name:
  • CD46
  • Gene Alias:
  • MCP,MGC26544,MIC10,TLX,TRA2.10
  • Gene Description:
  • CD46 molecule, complement regulatory protein
  • Gene Summary:
  • The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system. At least fourteen different transcript variants encoding fourteen different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • CD46 antigen, complement regulatory protein,OTTHUMP00000034577,OTTHUMP00000034622,OTTHUMP00000034623,OTTHUMP00000034624,OTTHUMP00000034625,OTTHUMP00000034626,OTTHUMP00000034706,antigen identified by monoclonal antibody TRA-2-10,complement membrane cofacto
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