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CD46 (Human) Recombinant Protein (Q01)

  • Catalog # : H00004179-Q01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human CD46 partial ORF ( AAH30594, 36 a.a. - 135 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 36.63
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00004179-Q01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 4179
  • Gene Name:
  • CD46
  • Gene Alias:
  • MCP,MGC26544,MIC10,TLX,TRA2.10
  • Gene Description:
  • CD46 molecule, complement regulatory protein
  • Gene Summary:
  • The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system. At least fourteen different transcript variants encoding fourteen different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • CD46 antigen, complement regulatory protein,OTTHUMP00000034577,OTTHUMP00000034622,OTTHUMP00000034623,OTTHUMP00000034624,OTTHUMP00000034625,OTTHUMP00000034626,OTTHUMP00000034706,antigen identified by monoclonal antibody TRA-2-10,complement membrane cofacto
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