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MCM6 Pre-design Chimera RNAi

  • Catalog # : H00004175-R02
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  • Specification
  • Product Description:
  • Homo sapiens MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) (MCM6), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_005915
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 4175
  • Gene Name:
  • MCM6
  • Gene Alias:
  • MCG40308,Mis5,P105MCM
  • Gene Description:
  • minichromosome maintenance complex component 6
  • Gene Summary:
  • The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. [provided by RefSeq
  • Other Designations:
  • DNA replication licensing factor MCM6,MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe),MIS5 homolog,minichromosome maintenance deficient (mis5, S. pombe) 6,minichromosome maintenance deficient 6 homolog
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