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MCM5 rabbit monoclonal antibody

  • Catalog # : H00004174-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human MCM5 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human MCM5 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human MCM5 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4174
  • GeneBank Accession#:
  • MCM5
  • Gene Name:
  • MCM5
  • Gene Alias:
  • CDC46,MGC5315,P1-CDC46
  • Gene Description:
  • minichromosome maintenance complex component 5
  • Gene Summary:
  • The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq
  • Other Designations:
  • DNA replication licensing factor,MCM5 minichromosome maintenance deficient 5, cell division cycle 46,minichromosome maintenance deficient 5 (cell division cycle 46)
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