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MCM4 (Human) Matched Antibody Pair

  • Catalog # : H00004173-AP21
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  • Specification
  • Product Description:
  • This antibody pair set comes with matched antibody pair to detect and quantify protein level of human MCM4.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Standard curve using recombinant protein ( H00004173-P01 ) as an analyte.

    QC Testing of H00004173-AP21
    Sandwich ELISA detection sensitivity ranging from 10 ng/ml to 100 ng/ml.
  • Supplied Product:
  • Antibody pair set content:
    1. Capture antibody: rabbit MaxPab® affinity purified polyclonal anti-MCM4 (100 ug)
    2. Detection antibody: mouse polyclonal anti-MCM4 (40 ul)
    *Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • ELISA Pair (Recombinant protein)
  • Gene Information
  • Entrez GeneID:
  • 4173
  • Gene Name:
  • MCM4
  • Gene Alias:
  • CDC21,CDC54,MGC33310,P1-CDC21,hCdc21
  • Gene Description:
  • minichromosome maintenance complex component 4
  • Gene Summary:
  • The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq
  • Other Designations:
  • DNA replication licensing factor MCM4,MCM4 minichromosome maintenance deficient 4,homolog of S. pombe cell devision cycle 21,minichromosome maintenance deficient 4
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