MC2R (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human MC2R full-length ORF ( NP_000520.1, 1 a.a. - 297 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVFKNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSHHVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLPRANMKGAITLTILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSPELRDAFKKMIFCSRYW
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
60.3
Interspecies Antigen Sequence
Mouse (89); Rat (90)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MC2R
Entrez GeneID
4158GeneBank Accession#
NM_000529.2Protein Accession#
NP_000520.1Gene Name
MC2R
Gene Alias
ACTHR, MGC125798
Gene Description
melanocortin 2 receptor (adrenocorticotropic hormone)
Gene Ontology
HyperlinkGene Summary
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. [provided by RefSeq
Other Designations
ACTH receptor|MC2 receptor|OTTHUMP00000162512|adrenocorticotropic hormone receptor|corticotropin receptor|melanocortin 2 receptor
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Interactome
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Pathway
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Disease
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