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Last updated: 2016/12/4

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MC2R rabbit monoclonal antibody

  • Catalog # : H00004158-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human MC2R peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human MC2R is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human MC2R peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4158
  • GeneBank Accession#:
  • MC2R
  • Gene Name:
  • MC2R
  • Gene Alias:
  • ACTHR,MGC125798
  • Gene Description:
  • melanocortin 2 receptor (adrenocorticotropic hormone)
  • Gene Summary:
  • MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. [provided by RefSeq
  • Other Designations:
  • ACTH receptor,MC2 receptor,OTTHUMP00000162512,adrenocorticotropic hormone receptor,corticotropin receptor,melanocortin 2 receptor
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