MC2R rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MC2R peptide using ARM Technology.
Immunogen
A synthetic peptide of human MC2R is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MC2R peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MC2R
Entrez GeneID
4158GeneBank Accession#
MC2RGene Name
MC2R
Gene Alias
ACTHR, MGC125798
Gene Description
melanocortin 2 receptor (adrenocorticotropic hormone)
Gene Ontology
HyperlinkGene Summary
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. [provided by RefSeq
Other Designations
ACTH receptor|MC2 receptor|OTTHUMP00000162512|adrenocorticotropic hormone receptor|corticotropin receptor|melanocortin 2 receptor
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