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Last updated: 2016/10/23
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MATK monoclonal antibody (M05), clone 2C5

  • Catalog # : H00004145-M05
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a partial recombinant MATK.
  • Immunogen:
  • MATK (NP_647612, 422 a.a. ~ 507 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgG2a Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00004145-M05
    Western Blot detection against Immunogen (35.2 KDa) .
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Application Image
  • Western Blot (Recombinant protein)
  • Gene Information
  • Entrez GeneID:
  • 4145
  • Gene Name:
  • MATK
  • Gene Alias:
  • Gene Description:
  • megakaryocyte-associated tyrosine kinase
  • Gene Summary:
  • The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • Csk-homologous kinase,Csk-type protein tyrosine kinase,HYL tyrosine kinase,hematopoietic consensus tyrosine-lacking kinase,hydroxyaryl-protein kinase,leukocyte carboxyl-terminal src kinase related,protein kinase HYL,tyrosine kinase MATK,tyrosine-protein k
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