MAT1A (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human MAT1A partial ORF ( NP_000420, 1 a.a. - 92 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMVDYQRVVRDTIKHIGY
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
35.86
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MAT1A
Entrez GeneID
4143GeneBank Accession#
NM_000429Protein Accession#
NP_000420Gene Name
MAT1A
Gene Alias
MAT, MATA1, SAMS, SAMS1
Gene Description
methionine adenosyltransferase I, alpha
Gene Ontology
HyperlinkGene Summary
This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency. [provided by RefSeq
Other Designations
OTTHUMP00000019971|S-adenosylmethionine synthetase
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Interactome
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Disease
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