MAN2A1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human MAN2A1 partial ORF ( NP_002363, 1045 a.a. - 1144 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
DIHLVNLRTIQSKVGNGHSNEAALILHRKGFDCRFSSKGTGLFCSTTQGKILVQKLLNKFIVESLTPSSLSLMHSPPGTQNISEINLSPMEISTFRIQLR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (80); Rat (74)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MAN2A1
Entrez GeneID
4124GeneBank Accession#
NM_002372Protein Accession#
NP_002363Gene Name
MAN2A1
Gene Alias
GOLIM7, MANA2, MANII
Gene Description
mannosidase, alpha, class 2A, member 1
Omim ID
154582Gene Ontology
HyperlinkGene Summary
This gene encodes a protein which is a member of family 38 of the glycosyl hydrolases. The protein is located in the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus. [provided by RefSeq
Other Designations
Golgi alpha-mannosidase II|golgi integral membrane protein 7|mannosidase, alpha type II|mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
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Interactome
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Pathway
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Disease
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