MAL 293T Cell Transient Overexpression Lysate(Denatured)
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Specifications
Transfected Cell Line
293T
Plasmid
pCMV-MAL full-length
Host
Human
Theoretical MW (kDa)
25.48
Interspecies Antigen Sequence
Mouse (87); Rat (89)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-MAL antibody (H00004118-B01) by Western Blots.
Western Blot
Lane 1: MAL transfected lysate ( 16.94 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
MAL transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — MAL
Entrez GeneID
4118GeneBank Accession#
BC000458Protein Accession#
AAH00458Gene Name
MAL
Gene Alias
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Gene Description
mal, T-cell differentiation protein
Omim ID
188860Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq
Other Designations
T-cell differentiation protein MAL|T-lymphocyte maturation-associated protein|myelin and lymphocyte protein
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Interactomes
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