MAGEB2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MAGEB2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human MAGEB2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MAGEB2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MAGEB2
Entrez GeneID
4113GeneBank Accession#
MAGEB2Gene Name
MAGEB2
Gene Alias
DAM6, MAGE-XP-2, MGC26438
Gene Description
melanoma antigen family B, 2
Omim ID
300098Gene Ontology
HyperlinkGene Summary
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq
Other Designations
DSS/AHC critical interval MAGE superfamily 6|OTTHUMP00000023098|melanoma-associated antigen B2
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Interactome
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