MAGEA5 monoclonal antibody (M01), clone 6A5
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MAGEA5.
Immunogen
MAGEA5 (NP_066387.1, 60 a.a. ~ 124 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GPLKSPQGASAIPTAIDFTLWRQSIKGSSNQEEEGPSTSPDPESVFRAALSKKVADLIHFLLLKY
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (32.89 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MAGEA5 is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — MAGEA5
Entrez GeneID
4104GeneBank Accession#
NM_021049.4Protein Accession#
NP_066387.1Gene Name
MAGEA5
Gene Alias
MAGE5, MAGEA4, MGC129526
Gene Description
melanoma antigen family A, 5
Omim ID
300340Gene Ontology
HyperlinkGene Summary
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq
Other Designations
MAGE-5a antigen|MAGE-5b antigen
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